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The Lancet Pharmacotherapy for adults with overweight and obesity: a systematic review and network meta-analysis of randomised controlled trials Qingyang Shi et al.

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Male C57BL/6J mice (3545 g, 15- to 23-weeks-old) fed HFD, HFD-32 (CLEA Japan, 57% of total calorie from fat), for 40100 days were used as the mouse model of diet-induced obesity

Brand-name options (Wegovy, Zepbound, Foundayo) are FDA-approved medications that have undergone FDA review
